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In vitro mutagenesis for resistance to nilotinib
| Von Bubnoff et al53 | Bradeen et al52 | Ray et al54 |
|---|---|---|
| K247N | ||
| L248V | L248V | |
| G250E | ||
| Q252H | Q252H | |
| Y253C | ||
| Y253H | Y253H | Y253H |
| E255K | E255K | E255K |
| E255V | E255V | |
| L273F | ||
| E282K | ||
| K285N | ||
| V289L | ||
| E292K | ||
| E292V | ||
| N297T | ||
| F311I | ||
| T315I | T315I | T315I |
| S349L | ||
| F359C | ||
| F359I | ||
| F359V | ||
| H375P | ||
| L384M | ||
| L387F | ||
| T406I | ||
| W470L |
