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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Eur J Neurosci. 2009 Jul 15;30(2):272–278. doi: 10.1111/j.1460-9568.2009.06827.x

Figure 3.

Figure 3

Somatodendritic dopamine overflow during reverse-dialysis of the MOR agonist DAMGO into the VTA of WT and MOR KO mice.

A – Time course of dialysate dopamine levels before and following reverse dialysis of DAMGO (50 μM; black circles – WT, white circles – KO) into the VTA. Data are expressed as the means ± S.E.M., n - number of animals in each experimental group (5 animals per group). Other details as in Fig. 2..B – Bar graphs of basal VTA dopamine levels in WT and MOR KO mice expressed as the means ± S.E.M. C – Bar graphs of AUC values for the dopamine response to DAMGO in WT and MOR KO mice expressed as the means ± S.E.M. * denotes a significant difference in DAMGO-induced dopamine responses between WT and KO animals (p ≤ 0.05).