Skip to main content
. 2009 Jul 27;37(17):5830–5837. doi: 10.1093/nar/gkp595

Figure 1.

Figure 1.

Secondary structure and mutagenesis of VA RNAI. Sequence and secondary structure of the TSΔ21 variant of VA RNAI (20), shown in the extended conformation with the alternate asymmetric internal loop structure as boxed inset. The VA RNAI terminal stem is omitted but the nucleotide numbering shown corresponds to the full-length RNA (nts 1–155). Three tetranucleotide sequences involved in key base-pairing interactions for these alternate structures are highlighted along with mutations made to generate the 67–70U (outline font) and 75,76G RNAs (dashed line box).