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Serum anti-dsDNA antibodies and IL-6 in LMP1+TRAF5+/+ and LMP1+TRAF5−/− mice. Serum was collected from LMP1−TRAF5+/+ (open squares), LMP1+TRAF5+/+ (closed triangles), and LMP1+TRAF5−/− (open triangles) mice of 3–4 months of age. The collected serum was used in ELISAs specific for total anti-dsDNA antibodies (A) or IgG-specific anti-dsDNA antibodies (B). The serum was also used in IL-6-specific ELISAs (C). The IL-6 data are representative of two independent experiments.
