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Spontaneous germinal centers in LMP1+TRAF5+/+ and LMP1+TRAF5−/− mice. Spleens were collected from LMP1−TRAF5+/+ (white bar), LMP1+TRAF5+/+ (black bar), and LMP1+TRAF5−/− (gray bar) mice of 3–4 months of age. The spleens were homogenized and stained with anti-B220 PerCp mAb and GL7 mAb. *, P < 0.005.
