Table 2.
Snps | rs1533428 |
rs12994401 |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Group | Discovery group |
Replication group |
Combined group |
Discovery group |
Replication group |
Combined group |
||||||
Case | Control | Case | Control | Case | Control | Case | Control | Case | Control | Case | Control | |
Phenotype (n) | 127 | 64 | 116 | 65 | 243 | 129 | 127 | 64 | 122 | 64 | 249 | 128 |
Risk allele (T) frequency, % | 59.06 | 30.47 | 57.76 | 33.08 | 58.44 | 31.78 | 41.34 | 12.50 | 41.39 | 7.81 | 41.37 | 10.16 |
Genotypic P Values | 6.16E−06 | 2.24E−05 | 1.58E−10 | 1.50E−08 | 3.86E−08 | 9.76E−16 | ||||||
Allelic P values | 1.55E−07 | 6.75E−06 | 4.90E−12 | 3.34E−09 | 1.21E−12 | 1.84E−20 | ||||||
Recessive P values | 3.32E−06 | 6.24E−06 | 4.07E−11 | 7.22E−09 | 2.75E−08 | 2.39E−16 | ||||||
Dominant P values | 1.1E−03 | 3.46E−02 | 8.79E−05 | 2.7E−03 | 2.52E−06 | 2.98E−08 | ||||||
ORhom | 7.86 | 5.74 | 6.7 | 33.15 | 36.67 | 34.93 | ||||||
[3.11, 19.85] | [2.35, 13.99] | [3.57, 12.73] | [4.42, 248.60] | [4.88, 275.27] | [8.40, 145.24] | |||||||
ORhet | 1.6 | 0.98 | 1.27 | 0.67 | 1.855 | 1.083 | ||||||
[0.79, 3.22] | [0.48, 2.00] | [0.77, 2.08] | [0.29, 1.55] | [0.74, 4.63] | [0.59, 1.99] | |||||||
PAR, % | 41.11 | 36.88 | 39.07 | 32.96 | 36.43 | 34.74 |