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. Author manuscript; available in PMC: 2009 Oct 13.
Published in final edited form as: Biochem Biophys Res Commun. 2007 Dec 3;366(1):104–109. doi: 10.1016/j.bbrc.2007.11.091

Figure 2. PGE2 and cPGI2 prevent TNF-α transcription and halt ongoing TNF-α transcription.

Figure 2

Nuclear run-on transcription was measured in Raw cells treated with 1 μg/mL LPS in the presence of DMSO/vehicle (B), 1 μM cPGI2 (C) or 1 μM PGE2 (F) for 6 h. Bars D, E, G: Raw cells were pretreated with1 μg/mL LPS for 6 h followed by addition of 1 μM cPGI2 (D, E) or 1 μM PGE2 (G) for 15 or 30 min.