Figure 4.
APJ localization by IHC staining in the developing rat GI tract (embryonic, early postnatal). APJ-containing cells (white arrow) in the rat stomach epithelium (panel A: stomach, P16) and smooth muscle layer (panel B: stomach, E21). Duodenal goblet cell (panel C: duodenum, E21) and non-goblet, flask-shaped cells (panel D: duodenum, E21) immunostained for APJ. Colonic goblet cells immunostained for APJ (panel E: colon, P16). APJ immunoreactivity was detected predominantly at the plasma membrane of enteric cells.