Fig. 7. Paired pulse paradigms in-vitro.
A. Paired pulse responses generated by 200 Hz (IPI 5 ms) applied to the alveus. Responses recorded extracellularly in the alveus (left) and CA1 pyramidal layer (right). Dot denotes stimulus artifact. B. Cellular field responses (AEP) demonstrated paired pulse inhibition above 100 Hz (IPI 10 ms), while alvear field responses (CAP) were unaffected by the paired pulse paradigm. Paired pulse amplitude ratio, (P2/P1). C. CAP and AEP width were unaffected by the paired pulse paradigm up to IPIs of 4 ms. Below an IPI of 4 ms, cellular (AEP) and axonal (CAP) paired pulse responses shown slight desynchronization. Paired pulse width ratio, (W2/W1).