Table 2.
Parameter | Sham lesion | 5,7-DHT lesion | ||
---|---|---|---|---|
Vehicle | d-Amphetamine | Vehicle | d-Amphetamine | |
Indifference point, T50 (s) | 15.9 ± 1.9 | 11.4 ± 1.3* | 14.8 ± 1.2 | 13.8 ± 1.5 |
Slope, ɛ | −5.0 ± 0.6 | −4.0 ± 0.4 | −4.7 ± 0.6 | −3.6 ± 0.7 |
Weber fraction | 0.28 ± 0.05 | 0.34 ± 0.06 | 0.28 ± 0.04 | 0.46 ± 0.09 |
p2 | 0.97 ± 0.01 | 0.94 ± 0.04 | 0.98 ± 0.01 | 0.94 ± 0.02 |
Overall response rate (responses min−1) | 47.3 ± 6.8 | 32.5 ± 7.3* | 47.0 ± 5.5 | 27.8 ± 4.7* |
*P < 0.05, significant difference from vehicle-alone condition