Table 3.

Effect of SKF-81297 on quantitative timing parameters and overall response rate (mean ± SEM)

Parameter	Sham lesion		5,7-DHT lesion
	Vehicle	SKF-81297	Vehicle	SKF-81297
Indifference point, T50 (s)	14.8 ± 2.0	7.8 ± 1.2*	14.1 ± 1.1	9.0 ± 1.4*
Slope, ɛ	−4.3 ± 0.5	−3.1 ± 0.5*	−4.6 ± 0.5	−2.6 ± 0.4*
Weber fraction	0.33 ± 0.06	0.51 ± 0.09*	0.28 ± 0.04	0.56 ± 0.07*
p2	0.98 ± 0.06	0.88 ± 0.03	0.98 ± 0.01	0.89 ± 0.03
Overall response rate (responses min−1)	49.3 ± 7.3	15.3 ± 1.9*	47.2 ± 5.6	15.8 ± 1.8*

*P < 0.05, significant difference from vehicle-alone condition