Table 1.
Changes on the esophageal and gastric histomorphometry in RE rats
Group | Damage protecting percentages (%) | Inflammatory cells infiltration in esophagus (%) | Thickness of mucosa in esophagus (μm) | Hemorrhage depth in stomach (mm) |
Controls | ||||
Sham | 1.23 ± 0.13 | 0.86 ± 0.7 | 261.89 ± 23.67 | 0.003 ± 0.005 |
RE | 12.72 ± 3.81b | 94.80 ± 4.07b | 20.81 ± 46.53b | 0.963 ± 0.343 |
α-tocopherol | 29.15 ± 10.23bc | 72.53 ± 1.17bd | 57.12 ± 43.83b | 0.19 ± 0.11bd |
LF extracts (mg/kg) | ||||
125 | 24.86 ± 4.8bd | 78.92 ± 10.42bc | 138.56 ± 48.8ad | 0.13 ± 0.08bd |
250 | 26.56 ± 8.8bc | 68.31 ± 10.79bd | 99.75 ± 85.6b | 0.18 ± 0.08bd |
500 | 46.41 ± 17.77bc | 56.11 ± 4.05bd | 118.64 ± 80.38ac | 0.25 ± 0.18bd |
Values are expressed mean ± SD of five rats;
P < 0.05 and
P < 0.01 compared to sham control;
P < 0.05 and
P < 0.01 compared to RE control; RE: Reflux esophagitis; LF: Lonicerae Flos.