Table 2.
Univariate and multivariate analyses of the carcinogenic factors for HCC in male patients with HCV cirrhosis
|
Univariate analysis |
Multivariate analysis |
||||||
| Variables | Number of patients | P-value1 | RR2 | 95% CI | P-value3 | RR2 | 95% CI |
| Age (yr) | |||||||
| ≥ 60 | 43 | P = 0.032 | 1.726 | 1.032-2.881 | P = 0.035 | 4.469 | 1.271-5.723 |
| < 60 | 42 | 1 | 1 | ||||
| Alcohol | |||||||
| Yes | 45 | P = 0.826 | 1.058 | 0.632-1.771 | NS (P = 0.676) | 0.877 | 0.473-1.025 |
| No | 40 | 1 | 1 | ||||
| Smoking | |||||||
| Yes | 36 | P = 0.566 | 0.863 | 0.517-1.440 | NS (P = 0.696) | 0.893 | 0.504-1.580 |
| No | 49 | 1 | 1 | ||||
| AST | |||||||
| ≥ 100 | 47 | P = 0.213 | 1.376 | 0.824-2.298 | NS (P = 0.151) | 1.863 | 0.797-4.350 |
| < 100 | 38 | 1 | 1 | ||||
| ALT | |||||||
| ≥ 100 | 46 | P = 0.805 | 1.064 | 0.643-1.763 | NS (P = 0.485) | 0.752 | 0.337-1.667 |
| < 100 | 39 | 1 | 1 | ||||
| γ-GTP | |||||||
| ≥ 80 | 41 | P = 0.509 | 1.182 | 0.714-1.954 | NS (P = 0.561) | 1.178 | 0.679-2.041 |
| < 80 | 44 | 1 | 1 | ||||
| Anti-HBc | |||||||
| Positive | 43 | P = 0.111 | 1.522 | 0.898-2.577 | NS (P = 0.099) | 1.609 | 0.914-2.835 |
| Negative | 42 | 1 | 1 | ||||
P-values were obtained by using the log-rank test;
RR were calculated by comparing classes with Cox regression analysis;
P-values were obtained by using Cox regression analysis. RR: Relative risks; CI: Confidence interval; NS: Not significant.