Table 1.
Timing of Light Exposure Sessions (L.E.S.) and individual phase shifts of the endogenous circadian rhythms of temperature (CBTmin) and melatonin (DLMOn25%, MP25%, DLMOff25%) in the bright light (BL), intermittent light (IBL) and very dim light (VDL) exposure groups. By convention, phase delays are negative (−) shifts, phase advances are positive shifts. Note that due to low amplitude of their CBT rhythms, phase shifts of CBTmin are not given for subjects 2008, and 2041, and the center of the light exposure sessions relative to CBTmin is not given for subject 2008. Due to missing blood samples, melatonin MP25% and DLMOn25% could not be calculated for subject 2056. Centers of the light exposure sessions and phase shifts are given in hours.
Initial Phase (clocktime) |
L.E.S. (clocktime) |
Center L.E.S. relative to |
Phase shift |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Subject Code | Gender | CBTmin | DLMOn25% | Beginning | End | CBTmin | DLMOn25% | CBTmin | DLMOn25% | MP25% | DLMOff25% |
Condition BL | |||||||||||
19a1 | F | 4:17 | 22:57 | 23:32 | 6:02 | −1.50 | 3.82 | −2.70 | −3.15 | −2.65 | −2.16 |
2006 | M | 3:27 | 20:55 | 21:57 | 4:27 | −2.25 | 4.28 | −2.45 | −2.70 | −2.05 | −1.40 |
2012 | F | 4:51 | 23:16 | 23:04 | 5:34 | −2.53 | 3.04 | −3.72 | −3.36 | −3.31 | −3.27 |
2036 | M | 6:50 | 23:26 | 23:01 | 5:31 | −4.57 | 2.83 | −2.03 | −2.92 | −2.76 | −2.60 |
2041 | F | 1:57 | 20:32 | 21:32 | 4:02 | −1.17 | 4.24 | - | −2.48 | −2.25 | −2.03 |
2043 | M | 5:23 | 22:50 | 23:04 | 5:34 | −3.07 | 3.48 | −4.02 | −3.72 | −3.54 | −3.36 |
Median | 04:34 | 22:53 | 23:03 | 5:33 | −2.39 | 3.65 | −2.70 | −3.03 | −2.71 | −2.38 | |
Mean±SD | 4:28±1:40 | 22:19±1:16 | 22:42±0:46 | 5:12±0:46 | −2.51±1.22 | 3.61±0.61 | −2.98±0.85 | −3.05±0.45 | −2.76±0.58 | −2.47±0.76 | |
SEM | 00:41 | 00:31 | 0:19 | 0:19 | 0.50 | 0.25 | 0.38 | 0.18 | 0.24 | 0.31 | |
Condition IBL | |||||||||||
19b9 | M | 8:10 | 23:51 | 23:06 | 5:36 | −5.82 | 2.49 | −1.18 | −2.12 | −2.71 | −3.28 |
19c4 | F | 4:50 | 22:22 | 23:06 | 5:36 | −2.48 | 3.97 | −1.43 | −2.88 | −2.43 | −1.98 |
2004 | M | 5:10 | 0:40 | 23:01 | 5:31 | −2.90 | 1.60 | −3.55 | −2.45 | −1.91 | −1.37 |
2024 | M | 5:31 | 22:48 | 22:58 | 5:28 | −3.30 | 3.42 | −1.73 | −2.14 | −1.64 | −1.12 |
2035 | M | 5:03 | 22:12 | 22:01 | 4:31 | −3.78 | 3.07 | −3.07 | −2.98 | −2.30 | −1.63 |
19c9 | M | 6:19 | 22:09 | 22:54 | 5:24 | −4.17 | 4.00 | −1.65 | −2.28 | −1.82 | −1.38 |
2042 | F | 3:47 | 23:23 | 22:01 | 4:31 | −2.52 | 1.87 | −3.65 | −2.34 | −2.43 | −2.52 |
Median | 5:10 | 22:48 | 22:58 | 5:28 | −3.30 | 3.07 | −1.73 | −2.34 | −2.30 | −1.63 | |
Mean±SD | 5:33±1:23 | 23:04±0:57 | 22:44±0:30 | 5:14±0:30 | −3.57±1.17 | 2.92±0.96 | −2.32±1.06 | −2.46±0.34 | −2.18±0.39 | −1.90±0.77 | |
SEM | 0:31 | 0:22 | 0:11 | 0:11 | 0.44 | 0.36 | 0.40 | 0.13 | 0.15 | 0.29 | |
Condition VDL | |||||||||||
19b1 | M | 6:17 | 0:10 | 23:32 | 6:02 | −3.50 | 2.61 | 0.47 | −0.33 | −0.46 | −0.58 |
19c3 | M | 6:08 | 23:39 | 23:43 | 6:13 | −3.17 | 3.31 | 0.42 | −0.52 | −0.19 | 0.13 |
2008 | F | 21:49 | 21:58 | 4:28 | - | 3.39 | - | −0.24 | 0.05 | 0.34 | |
2018 | M | 6:06 | 23:23 | 23:11 | 5:41 | −3.67 | 3.04 | 0.17 | −0.29 | −0.38 | −0.47 |
2038 | M | 6:08 | 22:32 | 22:24 | 4:54 | −4.48 | 3.11 | 1.32 | 0.06 | 0.19 | 0.33 |
2039 | M | 5:04 | 21:40 | 21:04 | 3:34 | −4.75 | 2.65 | 0.98 | −1.09 | −0.82 | −0.55 |
2056 | M | 8:10 | 0:26 | 0:02 | 6:32 | −4.88 | 2.84 | −0.25 | - | - | −0.93 |
Median | 06:08 | 23:23 | 23:11 | 5:41 | −4.07 | 3.04 | 0.44 | −0.31 | −0.28 | −0.47 | |
Mean±SD | 6:19±1:01 | 23:06±1:06 | 22:51±1:05 | 5:21±1:05 | −4.08±0.72 | 2.99±0.30 | 0.52±0.56 | −0.40±0.39 | −0.27±0.37 | −0.25±0.51 | |
SEM | 0:25 | 0:25 | 0:24 | 0:24 | 0.29 | 0.12 | 0.23 | 0.16 | 0.15 | 0.19 |