Table 3.
Gene SNP | Allele | n (%) | PIVKA-II1, ng/mL | p |
---|---|---|---|---|
VKORC1 rs17878544 | AA | 398 (96) | 2.19 (1.85–2.55) | |
AG | 18 (4) | 1.89 (1.36–2.43) | 0.233 | |
VKORC1 rs8050894 | CC | 152 (37) | 2.07 (1.70–2.45) | |
CG | 180 (44) | 2.26 (1.90–2.62) | ||
GG | 77 (19) | 2.07 (1.70–2.43) | 0.105 | |
VKORC1 rs7294 | GG | 156 (38) | 2.21 (1.84–2.50) | |
AG | 197 (47) | 2.15 (1.79–2.50) | ||
AA | 58 (14) | 1.99 (1.59–2.39) | 0.311 | |
GGCX rs10187424 | TT | 150 (36) | 2.13 (1.76–2.49) | |
CT | 198 (48) | 2.17 (1.81–2.53) | ||
CC | 68 (16) | 2.10 (1.71–2.49) | 0.793 | |
GGCX rs7568458 | AA | 137 (33) | 2.10 (1.75–2.47) | |
AT | 201 (48) | 2.18 (1.83–2.54) | ||
TT | 78 (19) | 2.11 (1.71–2.49) | 0.666 | |
GGCX rs699664 | GG | 212 (51) | 2.07 (1.72–2.43) | |
GA | 169 (40) | 2.17 (1.80–2.54) | ||
AA | 35 (8) | 2.28 (1.86–2.71) | 0.329 | |
GGCX rs2028898 | CC | 235 (56) | 2.10 (1.75–2.45) | |
CT | 160 (38) | 2.17 (1.80–2.54) | ||
TT | 21 (5) | 2.26 (1.78–2.74) | 0.583 |
Adjusted for age, gender, BMI, smoking, plasma triglycerides, dietary phylloquinone, ethnicity, and presented as mean (95% CI).