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Histological characteristic of injured aorta following Ad-CD39 transduction. Results are presented as mean±SD from 6–10 animals.
| Ad-CD39 (n=10) | Ad-β-Gal (n=6) | Saline (n=9) | |
|---|---|---|---|
| Intimal layer: | |||
| Thickness (µm) | 26.2±3.9 *** | 51.8±6.1 | 64.4±22.2 |
| Area (mm2) | 0.075±0.013 *** | 0.184±0.020 | 0.212±0.079 |
| Media layer: | |||
| Thickness (µm) | 120.6±14.8 | 111.4±11.5 | 108.6±16.6 |
| Area (mm2) | 0.438±0.093 | 0.458±0.077 | 0.431±0.060 |
| Intima/Media area | 0.17±0.03*** | 0.40±0.04 | 0.49±0.18 |
P<0.001 comparing to the saline group
