Table 1.
Characteristics of Participants According to Quintiles of Cord Blood Leptin (N=588)
| Variables | Total, Mean (SD) |
Quintile of Cord Blood Leptina | Trend P | ||||
|---|---|---|---|---|---|---|---|
| 1 (0.5–3.3) | 2 (> 3.3–5.5) | 3 (> 5.5–8.7) | 4 (> 8.7–13.9) | 5 (> 13.9–40.0) | |||
| Maternal variables | |||||||
| Age at enrollment, y | 32.3 (5.1) | 31.9 | 32.3 | 31.9 | 32.4 | 32.8 | .25 |
| Prepregnancy BMI, kg/m2 | 24.8 (5.4) | 24.2 | 24.1 | 24.7 | 25.1 | 26.0 | .003 |
| Gestational weight gain, kg | 15.7 (5.5) | 15.5 | 15.6 | 15.8 | 16.0 | 15.6 | .73 |
| Paternal BMI, kg/m2 | 26.4 (3.8) | 25.8 | 25.9 | 26.5 | 27.1 | 26.5 | .03 |
| Education,≥college degree | 400 (68)b | 69% | 67% | 64% | 65% | 75% | .45 |
| Married or cohabitating | 543 (93)b | 87% | 96% | 94% | 95% | 91% | .43 |
| Household income, more than $70 000 | 332 (61)b | 65% | 61% | 54% | 68% | 56% | .45 |
| Newborn/infant variables | |||||||
| Male | 295 (50)b | 65% | 58% | 52% | 42% | 34% | <.0001 |
| Race/ethnicity, white | 408 (69)b | 69% | 76% | 71% | 64% | 66% | .16 |
| Cord blood adiponectin,µg/mL | 28.5 (6.8) | 24.2 | 27.1 | 29.8 | 30 | 31.7 | <.0001 |
| Gestational age at birth, wk | 39.7 (1.5) | 38.9 | 39.7 | 39.7 | 40.1 | 40.1 | <.0001 |
| BW/GA, z score | 0.26 (0.94) | −0.15 | −0.08 | 0.16 | 0.50 | 0.84 | <.0001 |
| Breastfeeding duration, mo | 6.2 (4.5) | 6.2 | 5.6 | 6.5 | 5.6 | 7.3 | .08 |
| Child 3-y variables | |||||||
| Age, y | 3.3 (0.4) | 3.4 | 3.3 | 3.3 | 3.3 | 3.2 | .002 |
| BMI z score | 0.41 (1.03) | 0.42 | 0.32 | 0.52 | 0.53 | 0.24 | .61 |
| Weight-for-age z score | 0.45 (0.98) | 0.47 | 0.34 | 0.49 | 0.62 | 0.33 | .97 |
| Height-for-age z score | 0.27 (0.94) | 0.26 | 0.22 | 0.21 | 0.39 | 0.28 | .44 |
| Leg length, cm | 42.0 (3.1) | 42.5 | 41.7 | 42.0 | 42.1 | 41.8 | .30 |
| SS/TR ratio | 0.63 (0.15) | 0.62 | 0.62 | 0.64 | 0.64 | 0.64 | .19 |
| SS+TR, mm | 16.7 (4.2) | 16.9 | 16.2 | 16.4 | 17.4 | 16.7 | .63 |
| Leptin, ng/mL | 1.7 (1.8) | 1.3 | 1.4 | 1.8 | 1.8 | 2.2 | .001 |
| Adiponectin,µg/mL | 22.3 (6.0) | 23.3 | 22.9 | 22.5 | 21.0 | 21.4 | .02 |
Data are means unless otherwise specified.
Data are n (%).