Figure 5.

Spatial distribution of spike rate responses to flash in one of the experiments. Panel A shows the early change in spike rate (0–100 ms poststimulus minus baseline). Panel B shows the late change (150–1000 ms poststimulus minus baseline). Early responding units congregate in the monocular visual area (upper left area of the map); the distribution of late responding units is more widespread. Increasing desflurane exerts a differential effect on the early and late responses: the former is augmented whereas the latter is suppressed by the anesthetic in a concentration-dependent manner. The magnitude and spatial extent the responses appear to change in parallel.