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The domain structure of human AhR and CΔ553. bHLH, basic-helixloop-helix domains required for DNA binding; PAS, the Per/Arnt/Sim domains for dimeriztion; TAD, transactivation domain necessary for transcription activation; LBD, ligand binding domain. Full-length AhR consisting of 848 amino acids shown to compare with the truncated AhR CΔ553, which lacks part of PAS B, LBD, and TAD.
