Table 1.

Circadian Rhythm Regulatory Genes/Proteins

bHLH-PAS Family Members (basic Helix Loop Helix – Period/Arnt/Simpleminded)	bHLH-PAS Family Post-Translational Modifiers and/or Putative Downstream Targets
BMAL 1 & 2 (Bone and Muscle Arnt- Like)	CK1ε (Casein Kinase 1 ε)
Clock	Cry 1,2 (Cryptochrome)
DEC 1 & 2 (Differentially Expressed in Chondrocytes)	DBP (Albumin D site binding protein)
EPAS 1 (Endothelial PAS)	E4BP4
NPAS1 & 2 (Neuronal PAS)	GSK3β (Glycogen synthase kinase 3β)
Per 1,2,3 (Period) (PAS domain only)	Rev-Erb α & β