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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Proteins. 2009 Jul;76(1):13–29. doi: 10.1002/prot.22315

Table (IV).

Per amino acid agreements for the two-state scenario

PDB PDB
TM SOL avg TM SOL avg
pred UHS Guy
TM 70 ± 10 25 ± 7 81 49
SOL 30 ± 10 75 ± 7 19 51
73 ± 2 66
pred GES PM1D
TM 66 23 86 53
SOL 34 77 14 47
71 66
pred Janin PM3D
TM 72 32 83 52
SOL 28 67 17 48
70 66
pred KD HW
TM 76 39 89 59
SOL 24 61 11 41
68 65
pred WW EW
TM 48 13 88 60
SOL 52 87 12 40
67 64
pred HWvH
TM 11 1
SOL 89 99
55

The table shows the percentage per amino acid agreements for the two-state scenario between the prediction and the PDB for the hydrophobicity scales from the literature and the UHS. (TM) membrane bilayer; (SOL) soluble phase (SOL); (avg) average value of agreement between TM and SOL. The values are computed for a window size of 15 residues for averaging. The first four scales on the left show similar performances for the TM and the SOL, whereas the other scales exhibit an uneven distribution.