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. Author manuscript; available in PMC: 2009 Oct 14.
Published in final edited form as: Exp Neurol. 2008 Mar 25;211(2):539–550. doi: 10.1016/j.expneurol.2008.02.031

Figure 7. Quantification of motor target reinnervation at 150 days.

Figure 7

A. Uninjured EDL muscle demonstrates 100% motor endplate innervation. B. No endplate reinnervation was observed with atraumatic ETS repairs. C. A few motor endplates were reinnervated with compressive repair. D. The majority of remaining motor endplates were reinnervated with epineurotomy repair. E. Quantification of motor endplate reinnervation with atraumatic (Atraum), compression (Comp), and epineurotomy (Epi) ETS repairs. F. Retrograde-labeled femoral nerve ventral MNs at the L2-L4 spinal cord level in the atraumatic, G. compressive, and H. and epineurotomy ETS repairs. The femoral nerve now innervated the gastrocnemius, which was previouly innervated by the tibial nerve (S1–S2). I. Epineurotomy resulted in a significantly higher number of retrograde labeled ventral MNs originating at the L2–L4 levels, while atraumatic repair demonstrated occasional background, but statistically insignificant labeling (* p<0.05; ** p<0.0001). Scale bars 100 µm.