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. Author manuscript; available in PMC: 2009 Oct 14.
Published in final edited form as: Exp Neurol. 2008 Mar 25;211(2):539–550. doi: 10.1016/j.expneurol.2008.02.031

Figure 9. Assessment of MAG expression and CREB phosphorylation 21 days after ETS repair.

Figure 9

A. MAG expression was significantly downregulated in the compression group distal to the cuff and ETS repair site when normalized to GAPDH signal (* p<0.05). B. The number of nuclei with and without strong pCREB expression within the donor nerve immediately distal to the ETS repair. There were significantly fewer nuclei overall with relatively less pCREB expression in the atraumatic repair (**p<0.01) compared to all other groups. C1. Moderate colabeling in an atraumatic repair. C2. pCREB appears to colocalize with SCs (purple) enveloping axons (green). D. With proximal compression, a much higher percentage of nuclei express pCREB. E. With epineurotomy, pCREB also colocalizes with SCs surrounding axons.