Table 1. Statistical Analysis of the Inhibition of the CTMR Followed Intracutaneous Injection of Lidocaine Alone, QX-314 Alone, and a Combination of Lidocaine and QX-31.
ANOVA, post hoc | |||
---|---|---|---|
Drug | AUC (% × h) | 1% Lidocaine |
0.2% QX-314 |
1% lidocaine | 50.4 ± 4.7 | ||
0.2% QX-314 | 19.9 ± 9.1 | 0.825 | |
1% lidocaine + 0.2% QX-314 | 437.9 ± 62.0 | <0.001* | <0.001* |
P values obtained by one-way analysis of variance (ANOVA) and post hoc Dunnett's Test; n = 8.
P < 0.001.
AUC = area under curve; CTMR = cutaneous trunci muscle reflex.