Table 3. Comparison of Motor and Nociceptive Block after Perisciatic Injection of Different Concentrations of Lidocaine Alone, 0.2% QX-314 Alone, and a Combination of Lidocaine/QX-31.

Lidocaine Alone	0.5% Lidocaine	1% Lidocaine	2% Lidocaine
P value	0.72	0.725	0.878
0.2% QX-314	0.2% QX-314 alone	0.5% lidocaine + QX-314	1% lidocaine + QX-314	2% lidocaine + QX-314
P value	—§	0.005†	0.023*	< 0.001‡

P-value obtained by generalized estimating equations. n = 8.

^*P < 0.05;

^†P < 0.01;

^‡P < 0.001;

^§the algorithm failed to converge due to the single level of measured values (all 0).