Table 1.

TM topology predictors

Method	Version	TM pred.	SP pred.	Homology
TopPred	1.0	Yes	No	No
PHDhtm	2.1	Yes	No	Yes
HMMTOP	2.1	Yes	No	Yes
TMHMM	2.0	Yes	No	No
PolyPhobius	1.0	Yes	Yes	Yes
Memsat	3.0	Yes	Yes	Yes
SignalP	3.0	No	Yes	No

Features of the six TM topology predictors incorporated in MetaTM, plus the SP-only predictor SignalP.