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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Neuroscience. 2009 Aug 7;164(2):507–519. doi: 10.1016/j.neuroscience.2009.08.008

Figure 6. BDNF reduced intracellular accumulation of the δ subunit.

Figure 6

A-Intracellular accumulation of the δ subunit was studied in cultured hippocampal neurons using an antibody feeding technique. Representative neuron show reduced immunoreactivity for the δ subunit after BDNF treatment, which suggested a reduction in the intracellular accumulation of the δ subunit. B- Reduced intracellular accumulation of the δ subunit in the presence of BDNF was confirmed in the organotypic hippocampal slice cultures using a biotinylation method. A representative blots shows reduction in the amount of biotin-bound δ subunit in BDNF treated slices indicated reduced intracellular accumulation. Total expression of the δ subunit was similar in all the samples.