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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Neuroscience. 2009 Aug 7;164(2):507–519. doi: 10.1016/j.neuroscience.2009.08.008

Figure 8. BDNF effects were independent of network activity and mediated through activation of TrkB-Fc receptors.

Figure 8

A- Surface expression of the δ subunit was studied in hippocampal slice cultures treated with BDNF in the presence or absence of TTX (2 μM) for 6 hr. Surface (S) expression of the δ subunit was higher in TTX or BDNF treated slices. Total (T) expression of the δ subunit was similar in all the samples. B- Surface expression of the δ subunit was also studied in hippocampal slice cultures treated with BDNF in the presence of TrkB-Fc chimera (2 μg/ml). Surface expression (S) of the δ subunit was less in slices treated with BDNF and TrkB-Fc. Total expression (T) of the δ subunit was similar in all the samples. C- Surface expression of the δ subunit was expressed as a percent fraction of that in BDNF untreated control slices (n=3).