5HT concentration (A,C,E) and turnover (B,D,F) in frontal/parietal cortex (A,B), temporal/occipital cortex (C,D) and hippocampus (E,F). Data represent means and standard errors obtained from 6-12 animals in each group. ANOVA appears at the bottom of each panel and asterisks denote individual groups that differ significantly from the corresponding control. Daggers indicate significant differences between controls on the high-fat diet vs. normal diet. NS, not significant.