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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Neuroscience. 2009 Aug 19;164(2):832–841. doi: 10.1016/j.neuroscience.2009.08.022

Figure 2.

Figure 2

Effects of heme treatment on baseline luminescence in SCN explants from PER2∷LUC knockin mice. A, Example of a baseline (solid line) calculated as the 24 h. running average of the raw data (points) for a control SCN (left) and an SCN treated with 3 μM heme (right). B, Mean normalized baseline luminescence for control SCNs (0 μM, light gray line) and SCNs treated with 3 μM (dark gray line) or 30 μM (black line) heme binned every six hours. Horizontal lines indicate where 3 μM heme-treated (solid) and 30 μM heme-treated (dashed) groups differ statistically (p < .05) from the control (0 μM) group (one-way ANOVAs at each time point with Bonferroni correction, followed by Tukey’s HSD).