Fig. 3.
Analyses of metabolic functions in AAV8-hG6PT-infused GSD-Ib mice. Metabolic functions were analyzed in neonatally AAV8-hG6PT-infused GSD-Ib mice (−/−/AAV) during postnatal development. Age-matched unaffected (+/+) littermates were used as controls. (A) Serum glucose, cholesterol, triglyceride, uric acid, and lactic acid levels. N = 26 for each group. (B) The body weight of AAV8-hG6PT-infused GSD-Ib (●) and their unaffected (○) littermates during postnatal development. Data are presented as mean ± SEM. (C) The weights of the liver relative to total body weight. N = 10 for each group. *p < 0.05; **p < 0.005.