Table 1.

Membrane properties of prefrontal cortex neurons recorded in wild-type and heterozygous or homozygous dysbindin null mutant mice.

genotype	rheobase (pA)	spike threshold (mV)	spike amplitude (mV)	spike half-width (msec)	input resistance (mOhms)	cell capacitance (pF/cm2)	Holding current (pA)
wt/wt	135 +/− 7.2	−47.2 +/− 2.0	79.05 +/− 1.6	2.9 +/− 0.1	126.7 +/− 10.5	165.1 +/− 16.1	−178.2 +/− 21.5
wt/dys−	121.4 +/− 22.5*	−49.6 +/− 2.6*	78.2 +/− 3.9	2.2 +/− 0.1	118.6 +/− 12.9	79.5 +/− 19.8	−169.7 +/−36.2
dys−/dys−	67.1 +/− 11.7**	−56.7 +/− 1.5**	76.3 +/− 5.9	2.9 +/− 0.5	125 +/− 6.5	54.1 +/− 7.4	−192.4 +/− 40.9

Astrices indicate statistically significant differences between wild-type controls and mutant groups.

^*p<0.05

^**p<0.01.