Skip to main content
. Author manuscript; available in PMC: 2010 Oct 13.
Published in final edited form as: Curr Biol. 2009 Sep 17;19(19):1623–1627. doi: 10.1016/j.cub.2009.07.061

Figure 2.

Figure 2

Gr33a was essential for production of action potentials in response to aversive compounds. Shown are the results of tip recordings using s6 sensilla. (A) Representative traces of caffeine induced nerve firings between 50 and 550 milliseconds after application of the recording electrode. The flies used to test for rescue of the Gr33a mutant phenotype by the wild-type Gr33a+ transgene were: Gr33a1/Gr33aGAL4;UAS-Gr33a. The Gr33aGAL4 mutant allele did not show a response to caffeine (data not shown). (B-H) Quantification of the mean action potentials (spikes per second) induced by the indicated noxious chemicals. The genotypes are listed below. The means were based on data collected between 50 and 1050 ms after presentation of the compounds. The error bars represent SEMs. The data were analyzed using one-way ANOVA followed by Scheffe's post-hoc analysis. The asterisks indicate statistically significant differences from the Gr33a+ control (* P<0.05, ** P<0.01). Detailed statistics are presented in Table S3. See Figure S5 for dose response analyses, which include the data summarized in this figure.

HHS Vulnerability Disclosure