Table 4.
Multivariable logistic regression model comparing SIDS (sudden infant death syndrome) infants with high risk control infants. Values are numbers (percentages) unless stated otherwise
Factors | SIDS infants | High risk control infants | Multivariable odds ratio (95% CI)* | P value |
---|---|---|---|---|
Mother consumed >2 units† of alcohol in last 24 hours | 19/77 (25) | 3/82 (4) | 26.81 (4.36 to 164.99) | 0.0004 |
Infant shared parental bed or sofa for last sleep‡ | 43/79 (54) | 16/82 (20) | 10.07 (2.80 to 36.24) | 0.0004 |
Infant found prone for last sleep | 23/79 (29) | 7/81 (9) | 11.47 (2.29 to 57.56) | 0.003 |
Gestational age of infant ≤37 weeks | 21/80 (26) | 3/82 (4) | 11.17 (2.22 to 56.35) | 0.003 |
Infant swaddled for last sleep | 19/78 (24) | 3/82 (4) | 10.67 (2.14 to 53.29) | 0.004 |
Infant’s health in last 24 hours fair or poor | 22/79 (28) | 7/82 (9) | 6.53 (1.54 to 27.69) | 0.01 |
Infant (head or whole body) placed on pillow for last sleep | 16/78 (21) | 3/82 (4) | 8.47 (1.48 to 48.40) | 0.02 |
Infant slept in room without parent for last sleep‡ | 21/79 (27) | 17/82 (21) | — | 0.08 |
Apgar score <8 at 1 minute | 15/76 (20) | 6/79 (8) | — | 0.21 |
Infant admitted to neonatal intensive care unit at birth | 15/80 (19) | 2/82 (2) | — | 0.31 |
Infant appeared ill in last 24 hours | 26/80 (33) | 6/82 (7) | — | 0.41 |
Infant birth weight <2500 g | 13/80 (16) | 3/82 (4) | — | 0.44 |
Multivariable logistic regression model includes 74/80 SIDS cases (93%) and 81/82 controls (99%). Factors from variable infant sleeping in room without parent onwards were significant in univariable analysis but not significant in multivariable model; P value of these variables calculated by adding each variable to full model.
*Adjusted for infant’s age (P=0.77) and daytime or night time sleep (P=0.35), maternal smoking during pregnancy (P=0.18), maternal social class (P=0.04), young maternal age (P=0.86), and ≥3 live births (P=0.73) as well as other significant factors in multivariable model.
†Maximum recommended daily alcohol intake for women (United Kingdom): one unit is equivalent to one glass of beer (half pint), one small glass of wine, or one measure of spirits.
‡Multicategorical variable; infants who slept in a cot next to parental bed were reference group.