Table 1.

Two-bottle taste preference ratios from P2X2/P2X3^Dbl−/− mice and WT controls for multiple concentrations of denatonium benzoate and quinine

Denatonium			Quinine
Concentration (mM)	WT	P2X-KO	Concentration (mM)	WT	P2X-KO
0	0.44 ± 0.08	0.52 ± 0.08	0	0.54 ± 0.05	0.49 ± 0.03
0.3	0.26 ± 0.08*	0.64 ± 0.12*	0.1	0.17 ± 0.01*	0.51 ± 0.03*
3	0.12 ± 0.02*	0.42 ± 0.06*	0.3	0.16 ± 0.03*	0.51 ± 0.01*
30	0.18 ± 0.02	0.15 ± 0.02	1	0.22 ± 0.02*	0.49 ± 0.02*
			3	0.17 ± 0.05	0.29 ± 0.06
			10	0.22 ± 0.03	0.14 ± 0.02

A preference ratio of 0.5 indicates that the animals drank equally from the 2 bottles; numbers lower than 0.5 indicate avoidance of the tastant. Results are presented as the mean preference ratio ± standard error of the mean. Significant differences (P < 0.05) between KO and WT controls are indicated by an asterisk. Boldface shows values for KO mice that were significantly different from the non-preferred baseline. Our previous publication on the P2X2/P2X3^Dbl−/− mice (Finger et al. 2005) reported intake behaviors only up to a concentration of 3 mM for each substance.