Figure 4.

The constitutively active (Q70L) and wild-type rab11 do not inhibit recycling at 37°C of ¹²⁵I-transferrin molecules internalized during a previous incubation at 16°C, although the dominant negative form (S25N) of rab11 still inhibits recycling. This experiment was carried out as that in Fig. 3, except that the cells were loaded with ¹²⁵I-transferrin for 1 h by incubation at 16°C rather than at 37°C.