Table 1.
Monocyte subsets | Human monocyte | Murine monocyte | |||
---|---|---|---|---|---|
Adhesion cascade | CD14+ | CD16+ | Ly-6Chi | Ly-6Clo | |
Tethering/rolling | PSGL-1 | ++ | + | ++ | + |
L-selectin | + | − | + | − | |
E-selectin ligand | + | ? | + | ? | |
Adhesion | Mac-1 | + | + | + | + |
LFA-1 | + | + | + | + | |
VLA-1 | + | + | + | + | |
VLA-4 | + | + | + | + | |
Activation/migration | CCR1 | + | − | + | − |
CCR2 | + | − | + | − | |
CXCR1 | + | − | + | − | |
CXCR2 | + | − | + | − | |
CXCR4 | − | + | − | + | |
CCR7 | + | − | + | − | |
CX3CR1 | + | ++ | + | ++ |