Table 2.
Genotype and allele distributions in individuals with type 2 diabetes according to coronary artery disease status.
| Type 2 Diabetes |
|||
|---|---|---|---|
| SNP | CAD-Negative (n=412) | CAD-Positive (n=322) | p value |
| rs2383206 | |||
| A/A | 85 (20.6) | 41 (12.7) | |
| A/G | 208 (50.5) | 145 (45.0) | |
| G/G | 119 (28.9) | 136 (42.3) | 0.0002 |
| Allele G frequency† | 0.541 | 0.648 | 0.000048 |
| rs10757278 | |||
| A/A | 104 (25.3) | 56 (17.4) | |
| A/G | 209 (50.7) | 159 (49.4) | |
| G/G | 99 (24.0) | 107 (33.2) | 0.0049 |
| Allele G frequency† | 0.494 | 0.579 | 0.0013 |
†
Based on 824 chromosomes for the CAD-Negative group and 644 chromosomes for the CAD-Positive group.