TABLE 2.
One-year longitudinal assessment of body composition and adipose tissue distribution in patient participants who were able to maintain normal weight and in healthy control subjects1
| Patients (n = 16) |
Control subjects (n = 8) |
Comparison of patients and control subjects at follow-up |
|||
| Mean ± SD | P value2 | Mean ± SD | P value2 | P value3 | |
| Age (y) | 24.40 ± 5.62 | 27.00 ± 3.96 | |||
| Duration of illness (y) | 5.26 ± 3.39 | ||||
| Time between assessments (mo) | 10.75 ± 1.53 | 9.75 ± 2.19 | 0.204 | ||
| Weight (kg) | |||||
| Initial assessment4 | 53.85 ± 3.98 | 55.16 ± 5.20 | 0.277 | 0.611 | |
| Follow-up | 54.42 ± 7.07 | 55.91 ± 5.64 | |||
| Height (m) | 1.62 ± 0.06 | 1.65 ± 0.08 | |||
| BMI (kg/m2) | |||||
| Initial assessment4 | 20.47 ± 0.54 | 0.712 | 20.13 ± 0.80 | 0.270 | 0.734 |
| Follow-up | 20.70 ± 2.32 | 20.40 ± 1.00 | |||
| Percentage adipose tissue | |||||
| Initial assessment4 | 26.10 ± 4.60 | 0.52 | 24.05 ± 1.00 | 0.142 | 0.979 |
| Follow-up | 25.37 ± 7.13 | 25.29 ± 3.72 | |||
| SM (kg) | |||||
| Initial assessment4 | 17.40 ± 1.99 | 0.827 | 18.74 ± 2.23 | 0.517 | 0.328 |
| Follow-up | 17.30 ± 2.85 | 18.48 ± 2.44 | |||
| TAT (kg) | |||||
| Initial assessment4 | 14.07 ± 2.76 | 0.949 | 13.27 ± 2.54 | 0.064 | 0.937 |
| Follow-up | 14.01 ± 4.96 | 14.16 ± 2.71 | |||
| SAT (kg) | |||||
| Initial assessment4 | 12.62 ± 2.48 | 0.811 | 12.48 ± 2.14 | 0.094 | 0.806 |
| Follow-up | 12.84 ± 4.49 | 13.26 ± 2.38 | |||
| IMAT (kg) | |||||
| Initial assessment4 | 0.62 ± 0.26 | 0.114 | 0.29 ± 0.15 | 0.004 | 0.089 |
| Follow-up | 0.52 ± 0.26 | 0.35 ± 0.15 | |||
| VAT (kg) | |||||
| Initial assessment4 | 0.82 ± 0.29 | 0.096 | 0.50 ± 0.29 | 0.083 | 0.505 |
| Follow-up | 0.64 ± 0.35 | 0.54 ± 0.31 | |||
| Change in VAT between initial assessment and follow-up (g) | −180 ± 40 | 50 ± 7 | 0.044 | ||
| Percentage VAT (VAT/TAT) | |||||
| Initial assessment4 | 5.75 ± 1.58 | 0.07 | 3.57 ± 1.19 | 0.491 | 0.300 |
| Follow-up | 4.49 ± 1.76 | 3.72 ± 1.45 | |||
| Percentage SAT (SAT/TAT) | |||||
| Initial assessment4 | 89.80 ± 2.91 | 0.02 | 94.34 ± 1.77 | 0.077 | 0.030 |
| Follow-up | 91.84 ± 2.06 | 93.88 ± 1.93 | |||
| Percentage IMAT (IMAT/TAT) | |||||
| Initial assessment4 | 4.45 ± 1.82 | 0.01 | 2.09 ± 0.64 | 0.035 | 0.005 |
| Follow-up | 3.67 ± 1.40 | 2.40 ± 0.61 | |||
1
SM, skeletal mass; TAT, total adipose tissue; SAT, subcutaneous adipose tissue; IMAT, intermuscular adipose tissue; VAT, visceral adipose tissue.
2
Obtained by using paired t test to compare participants at initial assessment with those at follow-up.
3
Obtained by using independent samples t test.
4
Initial assessment for patient participants occurred 2–4 wk after reaching goal weight [BMI (in kg/m2) ≈19.5].