TABLE 3.

Associations between baseline measures of circulating osteocalcin and 3-y change in the homeostasis model assessment of insulin resistance (HOMA-IR) in older nondiabetic men and women (n = 162)¹

	Baseline (ln) uncarboxylated osteocalcin	Baseline percentage uncarboxylated osteocalcin	Baseline (ln) total osteocalcin	Baseline (ln) carboxylated osteocalcin
3-y change in HOMA-IR	0.20 ± 0.19	0.01 ± 0.01	−0.23 ± 0.39	−0.91 ± 0.29
P value	0.29	0.02	0.56	0.002
3-y change in insulin (mU/mL)	0.70 ± 0.65	0.05 ± 0.02	−0.82 ± 1.33	−2.99 ± 1.02
P value	0.28	0.03	0.54	0.004
3-y change in glucose (mg/dL)	−0.32 ± 1.26	0.04 ± 0.05	−2.70 ± 2.59	−4.24 ± 1.99
P value	0.80	0.34	0.30	0.03

¹All values are mean ± SE unstandardized B-coefficients and are calculated on the basis of multiple linear regression, adjusted for sex, age, race, baseline HOMA-IR, insulin or glucose, smoking, physical activity, percentage body fat at baseline, 3-y change in percentage body fat, serum 25-hydroxyvitamin D at baseline, and 3-y change in serum 25-hydroxyvitamin D.