Schematic representation of the experimental design. (A) Drawing showing the sites of capsaicin injection and behavioral testing in the hind paw. For capsaicin injection, a 27 gauge hypodermic needle was inserted intradermally at the heel of the foot (X) and advanced to the injection site (I), and capsaicin (20 μg in 20 μl olive oil) was injected. Primary and secondary hyperalgesia were measured at the areas marked ‘P’ and ‘S’, respectively. (B) Anatomical locations of 5 pairs of acupoints used in this study. EA was applied ipsilaterally to the capsacin-injected paw at the following pairs of points; GB30-GB34, BL40-BL60, GV2-GV6, LI3-LI6 and SI3-TE8.