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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Pain. 2009 Jul 30;145(3):332–340. doi: 10.1016/j.pain.2009.06.035

Fig. 6.

Fig. 6

Effects of intrathecal naltrexone on capsaicin-induced primary and secondary hyperalgesia. A and B show the effect of intrathecal NTX (10 μg in 30 μl saline) on EA-induced antihyperalgesic effect on the primary (A) and secondary (B) hyperalgesia. Naltrexone (or saline) was injected inthecally (i.t.) 10 min before termination of EA (20 min after start of EA). Data are expressed as means ± SEM. Number of animals - A and B: 8 in NTX and 7 in Saline groups. Data were analyzed by two-way repeated measure ANOVA, followed by the Holm-Sidak post hoc test. *, a value significantly (p<0.05) different from the corresponding value in the saline control group.