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. Author manuscript; available in PMC: 2010 Mar 26.
Published in final edited form as: J Med Chem. 2009 Mar 26;52(6):1530–1539. doi: 10.1021/jm8010993

Figure 1.

Figure 1

Effect of acute treatment of test compounds on immobility in the forced-swim test in ICR mice: (A) compound 14 (10 mg/kg, 37 µmol/kg and 30 mg/kg, 112 µmol/kg); (B) compound 19 (0.3 mg/kg, 1.0 µmol/kg and 3 mg/kg, 10 µµmol/kg) and (C) compound 21 (0.3 mg/kg, 0.5 µmol/kg and 3 mg/kg, 5 µmol/kg). Vehicle (Veh) or test agent was injected i.p. 30 min prior to the test. n = 9–11; * P < 0.05 vs. Veh.