Table I.
Detergent-Dependent Stability of BLT1 and BLT1His
| fos16 | fos12 | DDM | LDAO | DM | NG | OG | |
|---|---|---|---|---|---|---|---|
| BLT1 | 100 | 42 | 100 | 92 | 50 | — | — |
| BLT1His + Zn2+ | 100 | 96 | 100 | 98 | 95 | 89 | 73 |
Amount of ligand-competent receptor (expressed in % of total receptor) when BLT1 and BLT1His (in the presence of 1 mM Zn2+) were reconstituted in different detergents (fos16, fos-choline-16; fos12, fos-choline-12; DDM, dodecylmaltoside; DM, decylmaltoside; LDAO, lauryldimethylamine oxide; NG, nonylglucoside; OG, octylglucoside). Assays were all carried out at 20°C.