Figure 6.

X-ray Crystallographic cocrystal structure of the T-Mod(VMY)-MEEVF Complex. (A) The crystal structure of T-Mod(VMY) (gray ribbon) is shown in complex with the MEEVF peptide (blue sticks). Some of the side chains of T-Mod(VMY) involved in interactions with the peptide, including all residues varied in this work, are shown as sticks. (B) A 2F_o − F_c electron density map in the region of the MEEVF peptide. (C) Close-up view showing the interaction of the C-terminal phenylalanine side chain of the peptide with the hydrophobic pocket of the T-Mod. The side chains involved in the packing are shown as spheres representing van der Waals radii. These images were rendered in PyMol.