Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Oct 5;10:73. doi: 10.1186/1471-2121-10-73

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2009 Osses et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Alkaline phosphatase activity induced by inhibition of proteoglycan sulfation is not BMP-2 dependent. A. C2C12 cells were induced to differentiate in the presence of 5 nM BMP-2. ALP (open circles) and CK (closed circles) activity was determined as a function of time. The mean ± S.D. of two independent experiments performed in triplicate is presented. B. C2C12 cells were induced to differentiate in the presence of 5 nM BMP-2 and different concentrations of soluble BMP receptor IA (BMPR-IA_soluble). ALP (open circles) and CK (closed circles) activity was determined at day 6. Values presented as mean ± S.D. of two independent experiments performed in triplicate. C2C12 cells were induced to differentiate either in the absence (control) or presence of 30 mM sodium chlorate (chlorate) or 1 μg/ml soluble BMP receptor IA (BMPR-IA_soluble). ALP (C) and CK (D) activity was determined at day 8 days. The mean ± S.E.M, of two independent experiments performed in triplicate is presented. ANOVA analysis followed by Tukey-Kramer multiple comparisons test shows that there are no statistically significant differences (p > 0.05) within the control or chlorate conditions. All other comparisons are significantly different (p < 0.001).