Table 2.

Distribution of germline mutations in p16^CDKN2A and BRCA2 genes according to patients' origin

Analyzed gene Patients' origin	No. of analyzed patients	Positive cases
		No.	%
CDKN2A	846	16	1.9
non-Sardinian	545	16	2.9
Familial	35	6	17.1
Sporadic	510	10	2.0
Sardinian	301	0
Familial	10	0
Sporadic	291	0
BRCA2	455	4	0.9
non-Sardinian	154	0
Sardinian	301	4	1.3
North Sardinia	91	4	4.4
Familial	4	1	25.0
Sporadic	87	3	3.4
Middle-South Sardinia	210	0
Familial	6	0
Sporadic	204	0