After the registration is determined on the high resolution THRIVE images (see Figure 4), the detected transformation is applied to the lower resolution DCE-MRI data. The central slice for three time points before (column 1) and after rigid body registration (column 2), after the proposed algorithm (column 3), are shown. The three time points (t1, t2, and t3) correspond respectively to pre-treatment, post-one cycle of neoadjuvant chemotherapy, and after completion of chemotherapy.