Figure 3.
Treatment of undifferentiated MSCs with CQ extract in osteogenic media accelerates osteoblast differentiation: MSCs grown in osteogenic media alone show mild ALP activity by the 7th day of the treatment (A). Furthermore, MSCs grown in osteogenic media supplemented with 100, 200 or 300 μg/mL CQ extract show intense, dose-dependent ALP activity (B, C and D, respectively). Arrows indicate differentiating MSCs. Scale bar = 25 μm
