. Author manuscript; available in PMC: 2009 Oct 17.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2008 Jan 22;71(2):338–345. doi: 10.1016/j.ijrobp.2007.10.019

Table 2.

Comparison of acute and late toxicity between IMRT and ¹²⁵I seed monotherapy

Acute toxicity	IMRT	¹²⁵I	Fisher’s exact test
GI Grade 2	5/216 (2.3%)	3/158 (1.9%)	1.00
GI Grade 3	0 (0)	0 (0)
GU ≥ Grade 2	15/216 (6.9%)	42/158 (26.6%)	<0.0001^†
GU Grade 3	3/216 (1.4%)	6/158 (3.8%)	0.1758

Late toxicity^*			Log rank

GI Grade 2	2.4%	7.8%	0.0278
GI Grade 3	0.0%	0.1%	0.2276
GU ≥ Grade 2	3.5%	19.2%	<0.001
GU Grade 3	0.5%	5.6%	0.006
Urethral strictures	0	11/158 (7.0%)

Abbreviations: IMRT = intensity-modulated radiotherapy; GI = gastrointestinal; GU = genitourinary.

Three-year actuarial risk.

^†

Boldface = significant.